The Efficacy of Afamelanotide and Narrowband UV-B Phototherapy for Repigmentation of Vitiligo
نویسندگان
چکیده
منابع مشابه
The efficacy of afamelanotide and narrowband UV-B phototherapy for repigmentation of vitiligo.
BACKGROUND Vitiligo is characterized by depigmented patches of skin due to loss of cutaneous melanocytes. Many recent studies have demonstrated defects in the melanocortin system in patients with vitiligo, including decreased circulating and lesional skin levels of α-melanocyte-stimulating hormone (α-MSH). Afamelanotide is a potent and longer-lasting synthetic analogue of naturally occurring α-...
متن کاملParametric modeling of narrowband UV-B phototherapy for vitiligo using a novel quantitative tool: the Vitiligo Area Scoring Index.
BACKGROUND There is currently no quantitative tool for evaluating vitiligo treatment response using parametric methods. OBJECTIVE To develop and apply a simple clinical tool, the Vitiligo Area Scoring Index (VASI), to model the response of vitiligo to narrowband UV-B (NB-UV-B) phototherapy using parametric tests. DESIGN Prospective, randomized, controlled, bilateral left-right comparison tr...
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1. Perri R, Assi M, Talwalkar J, Heimbach J, Hogan W, Moore SB, et al. Graft vs host disease after liver transplantation: A new approach is needed. Liver Transpl. 2007;13:1092--9. 2. Burdick JF, Vogelsang GB, Smith WJ, Farmer ER, Bias WB, Kaufmann SH, et al. Severe graft-versus-host disease in a livertransplant recipient. N Engl J Med. 1988;318:689--91. 3. Yilmaz M, Ozdemir F, Akbulut S, Ersan ...
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BACKGROUND Narrow-band UVB is the most innovative steroid sparing treatment in atopic dermatitis. There are studies showing efficacy of Narrow-band UVB in childhood atopic dermatitis, but there is lack of clinical trials in the literature determining the length of remission. Therefore, we sought to highlight its efficacy, safety and its post-treatment efficacy in childhood atopic dermatitis. ...
متن کاملNarrowband ultraviolet B phototherapy and 308-nm excimer laser in the treatment of vitiligo: a review.
Vitiligo is a common and chronic disease with a great impact on patients' quality of life. Phototherapy with narrowband ultraviolet B radiation and excimer laser are two treatment modalities that are used increasingly for the management of the disease with variable results. In this article, we review the efficacy, adverse effects, and possible mechanisms of action of narrowband ultraviolet B an...
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ژورنال
عنوان ژورنال: JAMA Dermatology
سال: 2013
ISSN: 2168-6068
DOI: 10.1001/2013.jamadermatol.386